A follow-up to a momentous hormone replacement therapy (HRT) study on hormone use after menopause shows women who stopped taking the pills decreased risk of heart problems, but opened new doors for breast and lung tumors.
Some benefits for Prempro estrogen-protestin users include decreased risks for hip fractures and colorectal cancer, but the follow-up shows the hormones may have triggered new tumors or fueled the growth of existing ones in women who stopped taking hormones.
“There’s still a lot of uncertainty about the cause of the increased cancer risk,” said analysis co-author Dr. JoAnn Manson, chief of preventive medicine at Harvard’s Brigham and Women’s Hospital.
The analysis focused on participants’ health in the first two to three years after hormone pills were revoked, and during that time, those who’d taken hormones but stopped were 24 percent more likely to develop any kind of cancer than women who’d taken dummy pills during the study.
Some data suggest that U.S. breast cancer rates have declined since the study’s end and that hormones are still a very appropriate therapy for women with bad symptoms, but former hormone users need to be vigilant about getting cancer screening including mammograms.
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Some benefits for Prempro estrogen-protestin users include decreased risks for hip fractures and colorectal cancer, but the follow-up shows the hormones may have triggered new tumors or fueled the growth of existing ones in women who stopped taking hormones.
“There’s still a lot of uncertainty about the cause of the increased cancer risk,” said analysis co-author Dr. JoAnn Manson, chief of preventive medicine at Harvard’s Brigham and Women’s Hospital.
The analysis focused on participants’ health in the first two to three years after hormone pills were revoked, and during that time, those who’d taken hormones but stopped were 24 percent more likely to develop any kind of cancer than women who’d taken dummy pills during the study.
Some data suggest that U.S. breast cancer rates have declined since the study’s end and that hormones are still a very appropriate therapy for women with bad symptoms, but former hormone users need to be vigilant about getting cancer screening including mammograms.
Full Article
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